Cain Portrait
Character Information
Character Type Playable
Base Health
Heart flash
Heart bigHeart big
Base Damage
Dmg flash
Base Fire Rate
Tears flash
Base Range
Range flash
Base Speed
Speed flash
Base Shot Speed
Tear speed flash
Base Luck
Luck flash
Starting Pickups
Key x1
Starting Collectibles
Collectibles 046 luckyfoot
Unlocked By 55 Pennies Collected in One Run

Cain is a playable character in The Binding of Isaac: Rebirth.

He starts with the passive collectible Lucky Foot and one key. Cain has the highest movement speed out of all of the playable characters, but he is also one of the ones with the shortest range - tied with Azazel and Lazarus. Cain also has the highest luck stat out of all the playable characters.


  • Cain is a reference to the biblical figure Cain, firstborn son of Adam and Eve and he who committed the first murder, the victim being his brother Abel.
    • Abel can be found as an unlockable item, appearing as a dead, disembodied head.
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