The Catacombs is a variant to the second floor in The Binding of Isaac: Rebirth. It has two stages, The Catacombs I and The Catacombs II. It is unlocked when every boss in The Caves has been defeated.
- Mushrooms are found in The Catacombs. They will contain either nothing, Pills, Liberty Cap, or toxic gas.
|The Carrion Queen||Dark One||The Hollow||The Husk|
|Double Trouble Bosses|
|Dingle||The Duke of Flies||Gemini|
- The theme to The Catacombs, "Capiticus Calvaria", does have some meaning to it. While "calvaria" means skull, "capiticus" means nothing in Latin. However, the Latin word "caput" means "head" and "icus" means derived from or belonging to.
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